Predicting progression in PPMS
Submitted by art on Thu, 2008-04-17 08:52.
Rates of progression vary widely in PPMS. This study aimed to identify predictors of progression over 10 years. A total of 101 patients who had been imaged at baseline and 2 years were scored on the EDSS after 10 years. The study identified the following things that predicted progression: male sex, shorter disease duration, and slower timed walk test at baseline (best overall predictor), and deterioration in EDSS score and reduction in brain volume over 2 years.